Health & Fitness Scientific Reasons Why You Should Not Wear BRA While Sleeping Posted on April 20, 2017 by Hollie 4. Skin Irritation Avoid the excess use of underwire bra in order to prevent your skin from any kind of irritation. 5. Way to some serious health and fitness issue Avoid wearing bras at night while sleeping as it can cause the lymphatic blockage. Pages: 1 2 3 4